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Bioinformatics

WHAT IS BIOINFORMATICS?

Bioinformatics uses the combination of biology, mathematics, and computer science in order to analyze large collections of biological data. With the help of bioinformatics, scientists can better understand the genotype-phenotype connection for human disease, the structure to function relationship for proteins, and biological networks. The human body can be broken down into small machinery of cells that are controlled by a central processing unit called DNA. Understanding DNA can reveal a lot about the organism as well as the chances of diseases in future. Application of machine learning in bioinformatics has given rise to a lot of application from diseases prediction, diagnosis and survival analysis. Data Science has changed a lot in bioinformatics from dimensional reduction of large data sets to data visualization.

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BIOINFORMATICS IN:

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WHY ARE BIOINFORMATICS IMPORTANT?

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Bioinformatics has become a fundamental tool in biology. It is used to help scientists map the human genome computationally. Bioinformatics are important for research because they create databases that are needed to store information about genomes. In the field of genetics and genomics, it aids in sequencing and annotating genomes and their observed mutations. Bioinformatics plays a role in the textual mining of biological literature and the development of biological and gene ontologies to organize and query biological data. It plays a role in the analysis of gene and protein expression and regulation. Bioinformatics tools aid in the comparison of genetic and genomic data and more generally in the understanding of evolutionary aspects of molecular biology.

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BIOINFORMATICS IS USED IN:

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HOW BIOINFORMATICS IMPACT THE WORLD:

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Yen Nguyen

8333 Kingsbridge Dr, Sacramento, CA 95829

"Bioinformatic tools can now identify many silent biosynthetic gene clusters in bacterial genomes. The next step is figuring out how to activate them. 'That would profoundly change natural product discovery, and also drug discovery,' says Seyedsayamdost. Researchers have tried many..."

"Reasoning that different bacteria must have evolved different CRISPR systems and nucleases that might form the basis of more user-friendly tools, the team developed a bioinformatics program to search bacterial genome databases for previously unknown, more compact RNA-targeting Cas ribonuclease enzymes..."

"...they started investigating to see if the could identify which genes are turned on or off in the heart-like cells in the lung. This was challenging because they are a very small population of cells deeply embedded in the lung, they are hard to reach and hard to isolate to look at them so instead they examined publicly availiabvle data and mined it using bioinformatics..."

"More than 40,000 Americans die each year from this devastating disease, making it the third deadliest cancer nationwide. Most patients do not show signs of the illness until their cancers have spread elsewhere in the body, and even when caught early, pancreatic cancers do not respond well to treatment..."

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